We have all heard of nut allergies, pollen allergies, and even sun allergies, but has anyone ever come across a person allergic to water? This is an extremely rare condition where a person develops red, itchy hives, welts, and feels a burning sensation minutes after coming into contact with water 鈥 and no, the temperature of the water doesn’t matter. Sounds like a joke, right? Except 鈥 it鈥檚 real. And it鈥檚 called Aquagenic Urticaria.Fewer than 100 cases have been documented worldwide as of recent reviews, with some estimates citing around 77鈥100 total cases in the medical literature.A retrospective study of 296 children with chronic urticaria at a Northern India tertiary centre (2021) found just 4 cases of aquagenic urticaria鈥攖hat鈥檚 1.35% of all chronic urticaria cases in that group.H2O-No!Most of us come home sweaty and tired, and the moment we reach home, the first thing we do is go for a shower because it’s only natural to do so. But for someone with this condition, each of these everyday experiences can result in a very painful state; water itself is the problem, not the chlorine, minerals, or impurities in it.Dr Vaibhav Kalambe, Consultant Dermatologist at AIMS Hospital, Dombivli says that aquagenic urticaria is a rare condition where contact with water triggers hives. 鈥淚ts exact cause is unclear, but it may involve a hypersensitive skin reaction or immune response to water interacting with skin compounds,鈥 Dr Vaibhav says.It doesn鈥檛 matter where the water comes from, rain, tap, or bottled water 鈥 it all has the same effect. Even sweat or tears can trigger a painful skin reaction. In fact, crying can hurt as well. Which means heartbreak is now both emotional and physical.Believe the UnbelievableSo, how does one confirm if someone is allergic to water? 鈥淲e do something called a water challenge test,鈥 explains Dr. Kalambe. 鈥淲e apply water at room temperature to a small area of skin and observe for about 10 minutes. If hives or welts appear, it confirms the diagnosis.鈥漈here鈥檚 no fancy lab test or blood work.It鈥檚 all about observation. But because this condition is so rare 鈥攐nly a few cases are reported globally each year 鈥 it鈥檚 often misunderstood or missed altogether.Many patients go through months, even years, of confusion. They鈥檙e told they have eczema, allergies, anxiety, or 鈥渟ensitive skin.鈥 But the truth is far stranger than fiction. 鈥淚n India鈥檚 climate, managing sweat becomes a major challenge. Many patients have to adjust their whole lifestyle 鈥 what they wear, how they bathe, even what time they go outside. It takes a physical and emotional toll,鈥 says Dr Neeraj Ghosh, allergy specialist.Shower with CautionCurrently, there is no cure for aquagenic urticaria, but treatment and lifestyle adjustments can help patients live more comfortably. 鈥淎ntihistamines are the first line of defence,鈥 says Dr. Kalambe. 鈥淭hey help manage the allergic response. We also recommend barrier creams, which can protect the skin by forming a thin layer between it and the water.鈥漃hototherapy is another line of treatment which can help reduce the skin鈥檚 sensitivity. 鈥淧atients should stay cool and dry,鈥 Dr. Kalambe advises. 鈥淟ukewarm, quick showers and using barrier creams beforehand can reduce reactions.鈥滶xercising, swimming, dancing in the rain 鈥 things most people enjoy 鈥攃an become full-on nightmares. 鈥淎quagenic urticaria is so rare that many dermatologists might go their entire careers without seeing a case. But rare doesn鈥檛 mean impossible. The key is not to dismiss patient complaints just because they don鈥檛 fit a typical pattern. If someone repeatedly reports skin flare-ups after water exposure 鈥 especially with no identifiable allergen 鈥 we need to investigate,鈥 says Dr Anjali Menon, consultant dermatologist.Final SplashAquagenic urticaria doesn鈥檛 just impact the skin; it leaves the individual scarred mentally as well. Some patients resort to showering once every few days, cleaning with wet wipes, or skipping events where water exposure might happen. 鈥淲e haven鈥檛 had a patient at our hospital with aquagenic urticaria yet,鈥 says Dr. Kalambe, 鈥渂ut I think more awareness is needed. People with unexplained rashes after contact with water should speak to a dermatologist.鈥